雜志介紹

Xenobiotica雜志介紹

《Xenobiotica》是一本以English為主的未開放獲取國際優(yōu)秀期刊，中文名稱異生菌，本刊主要出版、報道醫(yī)學-PHARMACOLOGY & PHARMACY領域的研究動態(tài)以及在該領域取得的各方面的經驗和科研成果，介紹該領域有關本專業(yè)的最新進展，探討行業(yè)發(fā)展的思路和方法，以促進學術信息交流，提高行業(yè)發(fā)展。該刊已被國際權威數(shù)據(jù)庫SCIE收錄，為該領域相關學科的發(fā)展起到了良好的推動作用，也得到了本專業(yè)人員的廣泛認可。該刊最新影響因子為1.3，最新CiteScore 指數(shù)為3.8。

本刊近期中國學者發(fā)表的論文主要有：

• Effects of shuanghuanglian injection on the activities of CYP1A2, 2C11, 2D1 and 3A1/2 in rats in vivo and in vitro.

  Author: Shi Y¹, Xu J¹, Qiao Y¹, Zhang W¹, Liu D², Qin M¹, Liu G¹, Dong M².

• Pharmacokinetic study of the prokinetic ABCs liquiritigenin, naringenin and hesperitin following the oral administration of Si-Ni-San decoction to functional dyspepsia patients.

  Author: Huang X¹, Xu J¹, He J², Shi S¹, Yan H¹, Wang J³, Ren P^1,4.

• Pharmacokinetics behaviors of l-menthol after inhalation and intravenous injection in rats and its inhibition effects on CYP450 enzymes in rat liver microsomes.

  Author: Feng X¹, Liu Y¹, Sun X¹, Li A¹, Jiang X², Zhu X¹, Zhao Z^1,3,4.

• Effects of CYP2C11 gene knockout on the pharmacokinetics and pharmacodynamics of warfarin in rats.

  Author: Ye H¹, Sui D¹, Liu W¹, Yuan Y¹, Ouyang Z¹, Wei Y¹.

英文介紹

Xenobiotica雜志英文介紹

Xenobiotica covers seven main areas, including:General Xenobiochemistry, including in vitro studies concerned with the metabolism, disposition and excretion of drugs, and other xenobiotics, as well as the structure, function and regulation of associated enzymesClinical Pharmacokinetics and Metabolism, covering the pharmacokinetics and absorption, distribution, metabolism and excretion of drugs and other xenobiotics in manAnimal Pharmacokinetics and Metabolism, covering the pharmacokinetics, and absorption, distribution, metabolism and excretion of drugs and other xenobiotics in animalsPharmacogenetics, defined as the identification and functional characterisation of polymorphic genes that encode xenobiotic metabolising enzymes and transporters that may result in altered enzymatic, cellular and clinical responses to xenobioticsMolecular Toxicology, concerning the mechanisms of toxicity and the study of toxicology of xenobiotics at the molecular levelXenobiotic Transporters, concerned with all aspects of the carrier proteins involved in the movement of xenobiotics into and out of cells, and their impact on pharmacokinetic behaviour in animals and manTopics in Xenobiochemistry, in the form of reviews and commentaries are primarily intended to be a critical analysis of the issue, wherein the author offers opinions on the relevance of data or of a particular experimental approach or methodology