導(dǎo)語(yǔ)：如何才能寫(xiě)好一篇英語(yǔ)感謝信，這就需要搜集整理更多的資料和文獻(xiàn)，歡迎閱讀由公務(wù)員之家整理的十篇范文，供你借鑒。

篇1

感謝父母的英語(yǔ)感謝信范文一Parents,

Dear Mom and Dad, thank you for the upbringing of my ex. In my life on the road, you have given me in every possible way of an enhanced level of care and concern! I will take away my life on the road, I will repay you well! Thank you again! I love you!

Your Baby

感謝父母的英語(yǔ)感謝信范文二My dearest Mummy and Daddy,

Thank you very much for what you had given me, taught me,arranged for me,prepared for me,and those you had done on my behalf which I might have most probably forgotten or misunderstood in the past. I really would like to repay you with my whole soul and ability. I could not wait any longer to say to you, You are my sunshine,forever!

Take care,every moment,every step,every second!

Your kid.

感謝父母的英語(yǔ)感謝信范文三My dearest Mummy and Daddy,

What does family mean? It means Father And Mother, I Love You.

Thank you, father. For you broke the habit of smoking when mother was pregnant. You began to smoke when you was thirteen. But you gave up it for the health of mother and I.

Thank you, mother. Thank you for bearing the sharp pain of childbirth. Thank you for not only giving me food, clothes and a place to live but also educating me honest, confidence and love.

Maybe I wont be very rich in the future, but I will try my best to be a good person to pay back your love.

Thank you!

篇2

dear mr li,

i’m very excited to write to express my thanks to you. i am now a freshman of wuhan university, which i have been dreaming about. mr li, i still remember the days when you taught me english. my english has been improved greatly because of your creative work. however, at one time, the pressure of examinations, too much homework and the high expectations made me depressed. i was tired of the warning that if i didn’t do my best, i wouldn’t have the chance to go to college. thanks for your encouragement; if not, i wouldn’t have realized my dream. and now i really understand you. i wish more and more of your students could go to their ideal colleges. are you still so busy? how i miss you!

hoping to hear from you soon.

yours,

li hua

篇3

Dear Mr. xxx,

Thank you so much for meeting with me yesterday at xxxxx. I really enjoyed discussing the mechanical engineering internship (#254987) posted for this coming summer and learning more about Allied Aircraft. I believe that my skills and abilities mesh well with the requirements for the position.

As I mentioned during the interview, I am currently a junior in the mechanical engineering program here at Penn State. Through my course work, I have gained experience in project management, teamwork, and leadership. Additionally, my previous work experience as a shift manager at McDonalds has given me practical experience in utilizing problem-solving techniques and teambuilding skillsboth important qualities as indicated in the description of the internship position at Allied Aircraft.

I want to reiterate my strong interest in the position. Please feel free to contact me at xxx-xxx-xxxXif I can provide you with any additional information.

Again, thank you for the opportunity to interview with you and for your consideration. Please extend my appreciation to the rest of the interview team as well.

Sincerely,

xxx

英語(yǔ)面試感謝信范文二

Thank You For Interview II

Dear (Bosss Name),

Thank you so much for seeing me yesterday. The interview confirmed what others have told me -that (Company Name) would be a terrific place for someone with my skills and interests.

I am convinced that I could make an impact and add value as a (job title) in your department.

As we reviewed my background, I hope that you came to a similar conclusion. It was indeed a pleasure to discuss the opportunities with you. I thank you again for the opportunity and look forward to our next interaction.

Again, you can reach me (when) (Call time) at (telephone), or you may leave a message on my answering machine, and I will return your call promptly.

Sincerely,

(Signature)

英語(yǔ)面試感謝信范文三

Dear (Bosss Name),

Thank you so much for seeing me yesterday. The interview confirmed what others have told me - that (Company Name) would be a terrific place for someone with my skills and interests.

I am convinced that I could make an impact and add value as a (job title) in your department. As we reviewed my background, I hope that you came to a similar conclusion. It was indeed a pleasure to discuss the opportunities with you. I thank you again for the opportunity and look forward to our next interaction.

Again, you can reach me (when) (Call time) at (telephone), or you may leave a message on my answering machine, and I will return your call promptly.

篇4

有關(guān)于寫(xiě)給老師的英文感謝信范本1Dear Mr Li,

Im very excited to write to express my thanks to you. I am now a freshman of Wuhan University, which I have been dreaming about. Mr Li, I still remember the days when you taught me English.

My English has been improved greatly because of your creative work. However, at one time, the pressure of examinations, too much homework and the high expectations made me depressed. I was tired of the warning that if I didnt do my best, I wouldnt have the chance to go to college. Thanks for your encouragement; if not, I wouldnt have realized my dream. And now I really understand you.

I wish more and more of your students could go to their ideal colleges. Are you still so busy? How I miss you!

Hoping to hear from you soon.

Yours,

Li Hua

有關(guān)于寫(xiě)給老師的英文感謝信范本2Dear teacher ,

I am writing to you to express my thanks for your help in learning English and speaking English.

During these days in your class, I have learned much from you and it is very helpful to me. Firstly, you let me know what is the west thinking pattern—straight thinking pattern. And, I think, it is very important to understand the west’s thoughts. As you know, this can help me with my examination and interaction with foreigners. Secondly, I have got enough confidence in speaking in English from your class and it took me a long time to gain this confidence.

Now, I always express my ideas in English as possible as I can. It’s great to do that. The last not the least, I find that learning English is not an boring thing as before and I’m interested in studying English which was just a necessary task to pass examinations. Reading, listening or speaking all become interesting and I really enjoy it.

Above all, I want to say thanks again to you. And thank you for your time.

Good luck

有關(guān)于寫(xiě)給老師的英文感謝信范本3Dear Teacher:

This is a special day, we have presented a bouquet of flowers, gifts to the world of your peaches and plums, spectrum a Ode to Joy, for your eyes flicker disperse tired, for you loosen the amount of wrinkled patterns.

The singing is to thank: the teacher, thank you! Thank you do not make learning to become crafts, but have become a kind of joy; Thank you for letting me know their value; Thank you for helping me find their expertise, but let me do things better; Thank you for being one I can never trust people - will be in trouble in their lives to help people.

The singing is a blessing: teacher, happy holidays! Insatiable in learning, be tireless in teaching, peaches and plums fragrance, their music is happy and harmonious. I wish you a happy holiday! Not only in the Teacher's Day today, there is a tomorrow, the day after tomorrow, Tai Houtian, I wish your life every day, every minutes, every second, the surface is always the same smile.

The singing is concerned about: the teacher, you worked hard! Your use of sweat, nurturing the tender shoots of spring have just ground-breaking. Your care is like the genial spring, warm our hearts and minds. Let us protect your healthy growth, formed in the autumn fruit.

篇5

大三下學(xué)期，我開(kāi)始忙于在校外的實(shí)習(xí)，英語(yǔ)又被晾在了一邊。事實(shí)上，當(dāng)時(shí)我產(chǎn)生了破罐子破摔的心理。我想，反正人又不是靠英語(yǔ)活著呢，考不上就考不上唄，憑著自己其他方面的能力總能養(yǎng)活自己的?？上攵乙?0來(lái)分的成績(jī)結(jié)束了第三次征程。說(shuō)實(shí)話(huà)，我浪費(fèi)的不僅是這三次機(jī)會(huì)，更重要的是花在英語(yǔ)學(xué)習(xí)上的時(shí)間以及被英語(yǔ)所籠罩的心理陰影。試想一下，假如我珍惜機(jī)會(huì)，努力學(xué)習(xí)的話(huà)，也許我第一次或者第二次就會(huì)過(guò)關(guān)的。這樣我就可以把大把的時(shí)間用在其他方面上。不幸的是，我一次又一次的浪費(fèi)機(jī)會(huì)，換來(lái)的只是惡性循環(huán)。

大四的情況不同了，因?yàn)槲乙鎸?duì)更嚴(yán)峻的工作問(wèn)題。以前，家里對(duì)我基本上是放任自流的，很少過(guò)問(wèn)我學(xué)習(xí)上的事情。這次，哥哥逼著我要耐下心來(lái)學(xué)好英語(yǔ)。因?yàn)樗械饺绻矣⒄Z(yǔ)不過(guò)關(guān)的話(huà)，畢業(yè)時(shí)就不是學(xué)士學(xué)位，戶(hù)口也不能落在深圳或廣州等大城市。為此，他甚至要求我把英語(yǔ)以外的事情都放下來(lái)，專(zhuān)心學(xué)習(xí)英語(yǔ)。 這樣，我被分在了暑期班上。在學(xué)習(xí)中，與我年齡相差無(wú)幾的老師們的細(xì)致、活波的授課對(duì)我?guī)椭醮蟆＝?jīng)過(guò)在暑期四級(jí)強(qiáng)化班的系統(tǒng)學(xué)習(xí)，我在英語(yǔ)學(xué)習(xí)方法和技能上都有很大的提高。這一點(diǎn)在我做歷年四級(jí)真題和模考題上就明顯的顯示了出來(lái)。

老師們負(fù)責(zé)耐心細(xì)致的講解對(duì)我尤其幫助最大。你們不僅在課上為我們細(xì)致講解有關(guān)問(wèn)題，下課后從不早早走出教室，而是耐心地等待我們問(wèn)問(wèn)題，直到?jīng)]有人問(wèn)你們問(wèn)題后才離開(kāi)。我想說(shuō)，好人兩個(gè)字是最能概括你們的全部。

也許扯的有點(diǎn)遠(yuǎn)了，但歷經(jīng)磨難最終過(guò)了四級(jí)后的我的心情是很激動(dòng)的，所以就多說(shuō)了點(diǎn)，老師們不要見(jiàn)怪。

出成績(jī)的當(dāng)天，我匆匆洗完澡后，打開(kāi)查分的網(wǎng)頁(yè)，然后下載了一張耶穌的畫(huà)像，并把它設(shè)置成我的桌面。最后呆呆地坐在電腦桌前，閉上雙眼，合上雙手，做起了長(zhǎng)達(dá)一個(gè)小時(shí)的祈禱。雖然我不信基督教，但我腦中卻始終默念著神啊，拯救我吧，因?yàn)槲业膬?nèi)心充滿(mǎn)了擔(dān)憂(yōu)的急切的渴望。我把上帝作為了我當(dāng)時(shí)心靈上唯一幫助。當(dāng)其他宿舍傳來(lái)叫喊聲時(shí)，我知道能夠查分了。于是在網(wǎng)頁(yè)上輸入準(zhǔn)考證號(hào)后，我又閉上了雙眼，又默念了一句神啊，拯救我吧。當(dāng)睜開(kāi)眼時(shí)，我立刻欣喜若狂了起來(lái)，因?yàn)樯厦骘@示的是66.5分。據(jù)我同宿舍的哥們說(shuō)，我當(dāng)時(shí)的尖叫聲跟一個(gè)柔弱的女孩子突然見(jiàn)到一個(gè)可怕的毒蛇爬到腳下時(shí)沒(méi)有什么區(qū)別。

篇6

英語(yǔ)四級(jí)感謝信寫(xiě)作講解：

1. 格式要正確。與其他應(yīng)用文寫(xiě)作一樣，書(shū)信體裁需要在正文的前面加上稱(chēng)呼，在正文的末尾加上結(jié)束語(yǔ)，落款和署名。

2. 標(biāo)點(diǎn)符號(hào)要正確。Dear+稱(chēng)謂的后面一定要用逗號(hào)，不能用冒號(hào)。還要注意英語(yǔ)的句號(hào)是實(shí)心的，并且涉及到書(shū)名、電影名或者作品名的，要大些，英語(yǔ)中沒(méi)有書(shū)名號(hào)。

3. 考生需要根據(jù)題目要求完成寫(xiě)作。在這一部分，考生需要注意字?jǐn)?shù)的要求是120-180字，不能少些或者超出。另外，雖然題目中并未對(duì)落款人作過(guò)多要求，但是考生還是有必要把敏感的人名、地名和學(xué)校名去掉，以防作弊嫌疑。

4. 通過(guò)三個(gè)題目的要求，我們都要明確表明我們的感激之心，表述時(shí)要目標(biāo)明確，語(yǔ)言貼切、充分，內(nèi)容言之有物，句子流暢地道。

英語(yǔ)四級(jí)感謝信真題1：感謝朋友

For this part, you are allowed 30 minutes to write a letter to express your thanks to one of your friends who helped you most when you were in difficulty. You should write at least 120 words but no more than 180 words.

英語(yǔ)四級(jí)感謝信真題1范文：

Dear parents,

This letter is to tell you my true feelings from the bottom of my heart. Although we can keep in virtual touch every day, I still feel it not enough to let you know how much I love you and how much Ive appreciated what youve done for me.

In the past 20 years, you have done a lot for me. Firstly, thank you so much for bringing me up. I know how hard youve being working in the past. I can imagine how many difficulties and obstacles youve conquered. Second, I want to thank you for your good education on me. There is an old saying goes like this parents are the first teachers to their children. Both of you are the typical ones. The most important thing that I want to say thank you is for your great admiration on my own freedom. You told me to look over the horizons and to pursuit my own dreams without hesitation.

I really feel that my pen fails me when I am writing this thank you letter. The only thing I hope you can do for me is to take good care of yourselves and you will be always proud of me.

Yours beloved

Son

英語(yǔ)四級(jí)感謝信真題2范文：

Dear Mary,

I would like to take this opportunity to express my heartfelt gratitude to you for your help when I was in difficulty. You have been very kind and helpful since we knew each other.

Last week, I caught a bad cold and had to stay at home for a week. When I was worrying about the lessons, you came to my home after school and helped me with every subject. With your help, I didnt fall behind others.

Again, thanks so much for your enthusiastic help. Even though you are to about to go abroad for further education I know that I will always stay in touch with you. I wish you every success in the future and I hope we can exchange more viewpoints on study.

Please keep in touch, and drop in and visit us whenever you are in this part of the world.

Very sincerely

Peter

英語(yǔ)四級(jí)感謝信真題2：感謝老師

Directions: For this part,you are allowed 30 minutes to write a letter to express your thanks to your parents or any other family member upon making a memorable achievement. You should write st least 120 words but no more than 180 words.

英語(yǔ)四級(jí)感謝信真題3范文：

Dear sir,

I am writing to you to express my thanks for your help in learning English. You are one of the best teachers who I have ever met .There are many good points that I learn from you.

During these days in your class, I have acquired much knowledge from you and it really helps me a lot. Firstly, you let me know what the west thinking pattern is -straight thinking pattern. As an English learner, it is important for me to understand the difference between them. Whats more, Im glad to be your student, and I am very happy to learn the course under your guidance. English is an important tool, through which we can share our experience with the world. I treasure the chance of learning English, and I enjoy the happiness from your course.

The last not the least, please forgive those mistakes I have made which may upset you. What I have learned from you will help me pass the coming examinations and also be useful for my further education in abroad. It is not only a progress of learning, but also a cultivation of my ability.

May everything goes well around you.

Your student,

Li ling

篇7

新生兒腹瀉是由多種病原多種因素引起的，以大便次數(shù)增多和大便性狀改變?yōu)樘攸c(diǎn)的一組消化道綜合征【1】。主要是由于新生兒消化系統(tǒng)發(fā)育不成熟，生長(zhǎng)發(fā)育快，機(jī)體防御功能差，腸道菌群失調(diào)等因素造成的【2】。因此，在積極治療疾病的同時(shí)，給予積極完善的護(hù)理干預(yù)措施可以促進(jìn)患兒的康復(fù)。對(duì)我兒科2013年1月-2013年12月收治的新生兒腹瀉患兒給予護(hù)理干預(yù)措施，取得滿(mǎn)意效果，現(xiàn)將護(hù)理干預(yù)措施報(bào)道如下。

1 資料與方法

1.1 一般資料

選取2013年1月-2013年12月在我兒科治療的新生兒腹瀉患兒240例作為研究對(duì)象，隨機(jī)分成對(duì)照組和觀察組，對(duì)照組120例，其中男78例，女42例；年齡6d-24d，平均年齡14.1±0.6d；腹瀉次數(shù)5-14次，每次45-190ml。觀察組120例，其中男74例，女46例；年齡11d-23d，平均年齡15.3±0.6d；腹瀉次數(shù)4-15次，每次40-180ml。所有患兒入院后均經(jīng)大便常規(guī)檢查顯示，白細(xì)胞（++-+++），脂肪球（+-++），均符合新生兒腹瀉的診斷標(biāo)準(zhǔn)【3】。所有患兒家屬均簽署知情同意書(shū)。兩組患兒在年齡、性別、腹瀉次數(shù)方面無(wú)統(tǒng)計(jì)學(xué)意義（P>0.05），具有可比性。

1.2護(hù)理方法

1.2.1 對(duì)照組給予常規(guī)護(hù)理措施。

1.2.2 觀察組給予護(hù)理干預(yù)措施。

1.2.2.1 嚴(yán)密觀察患兒病情變化

患兒入院后嚴(yán)密觀察患兒的體溫、呼吸、脈搏等生命體征，準(zhǔn)確記錄患兒大便的次數(shù)、顏色、形狀等，有無(wú)低鉀、低鈣等電解質(zhì)紊亂癥，有無(wú)脫水及其脫水的程度，對(duì)于脫水程度不重的患兒給予口服補(bǔ)液鹽，服用方法：體重（kg）*75ml=用量ml/d；對(duì)于脫水嚴(yán)重且伴有代謝性酸中毒的患兒給予靜脈補(bǔ)液，補(bǔ)液時(shí)準(zhǔn)確計(jì)算補(bǔ)液總量補(bǔ)液成分和補(bǔ)液速度。

1.2.2.2 飲食護(hù)理

要根據(jù)患兒的腹瀉、嘔吐、食欲和消化情況，確定飲食的方法，對(duì)嘔吐、腹瀉嚴(yán)重患兒可暫時(shí)禁食6-8h，以利腸道休息，減少?lài)I吐及腹瀉次數(shù)，一般不禁水，行母乳喂養(yǎng)的新生兒應(yīng)持續(xù)喂哺母乳；對(duì)于人工喂養(yǎng)的腹瀉較重的新生兒，要減少奶量并用水稀釋?zhuān)捎?份牛乳加1/2份水，待腹瀉好轉(zhuǎn)后逐漸增加至全奶。當(dāng)患兒腹瀉好轉(zhuǎn)時(shí)，可以按照從稀到稠、從軟到硬的規(guī)律逐漸過(guò)渡的原則，少量多餐。

1.2.2.3 健康教育

首先宣傳母乳喂養(yǎng)的優(yōu)點(diǎn)，避免在夏季斷乳；新生兒的奶瓶用前應(yīng)煮沸消毒20分鐘，吃剩的奶液應(yīng)倒掉；母親應(yīng)保持乳房的清潔，勤換內(nèi)衣，盡量減少感染的機(jī)會(huì)；對(duì)于母乳不足可采取混合喂養(yǎng)及人工喂養(yǎng)的辦法，但是要注意飲食調(diào)配，避免發(fā)生碳水化合物消化不良，影響寶寶生長(zhǎng)發(fā)育；同時(shí)注意新生兒腹部的保暖，避免受涼。

1.3 觀察項(xiàng)目

對(duì)比分析兩組患兒的治療效果和患兒家屬滿(mǎn)意度。

1.4 療效評(píng)定標(biāo)準(zhǔn)

采用姚鳳一，陳凡【4】等評(píng)定標(biāo)準(zhǔn)，采用非常滿(mǎn)意（80-100分）、滿(mǎn)意（60-79分）和不滿(mǎn)意（

1.5 統(tǒng)計(jì)學(xué)方法

應(yīng)用SPSS17.0對(duì)數(shù)據(jù)進(jìn)行分析，計(jì)數(shù)資料采用χ 2檢驗(yàn)，計(jì)量資料比較采用t檢驗(yàn)，P

2 結(jié)果

2.1 兩組患者的治療效果比較

實(shí)施護(hù)理干預(yù)后，觀察組總有效率為94.2%，對(duì)照組總有效率為70.8%，觀察組的治療效果明顯優(yōu)于對(duì)照組，兩組比較差異有統(tǒng)計(jì)學(xué)意義（P

表1兩組患兒的臨床治療效果比較[n（%）]

組別 例數(shù) 顯效（例） 有效（例） 無(wú)效（例） 總有效率（%）

觀察組 120 91（75.8） 22（18.3） 7（5.8） 113（94.2）

對(duì)照組 120 46（38.3） 39（32.5） 35（29.2） 85（70.8）

X? 3.132 3.151 3.164 3.217

P值 P

2.2 兩組患兒家屬滿(mǎn)意度比較

實(shí)施護(hù)理干預(yù)后，觀察組的患兒家屬滿(mǎn)意度為98.3%，對(duì)照組的患兒家屬滿(mǎn)意度為74.2%，觀察組明顯優(yōu)于對(duì)照組，兩組比較差異有統(tǒng)計(jì)學(xué)意義（P

見(jiàn)表2

表2兩組患兒家屬滿(mǎn)意度比較[n（%）]

組別 例數(shù) 滿(mǎn)意（例） 基本滿(mǎn)意（例） 不滿(mǎn)意（例） 總滿(mǎn)意度（%）

觀察組 120 97（80.8） 21（17.5） 2（1.7） 118（98.3）

對(duì)照組 120 57（47.5） 32（26.7） 31（25.8） 89（74.2）

X? 3.242 3.272 3.261 3.286

P值

篇8

如何寫(xiě)感謝信？

感謝信的寫(xiě)作格式是書(shū)信體。寫(xiě)作時(shí)應(yīng)篇幅短，中文200字左右即可；對(duì)收信人為自己做的好事了然于胸，不要忘了什么；把對(duì)方給你帶來(lái)的好處都寫(xiě)清楚，不要含糊其詞；表示感謝的話(huà)要合乎商家往來(lái)的習(xí)慣，語(yǔ)氣不應(yīng)過(guò)于卑屈。謝意之外，如果允許別人什么應(yīng)切實(shí)可行，能說(shuō)到做到。

相關(guān)的感謝信樣本

·英語(yǔ)感謝信 ·國(guó)家助學(xué)金感謝信 ·寫(xiě)給學(xué)校的感謝信

·見(jiàn)義勇為感謝信 ·拾金不昧感謝信范文 ·面試后的感謝信

感謝信范文

xxxxxxx有限公司于xx年x月x口在南京舉行隆重開(kāi)業(yè)典禮，此間收到全國(guó)各地許多同行、用戶(hù)以及外國(guó)公司的賀電、賀函和賀禮。上級(jí)機(jī)關(guān)及全國(guó)各地單位的領(lǐng)導(dǎo)，世界各地的貴賓，國(guó)內(nèi)最著名的xxx線(xiàn)路專(zhuān)家等親臨參加慶典，寄予我公司極大的希望，謹(jǐn)此一并致謝，并愿一知既往與各方加強(qiáng)聯(lián)系。進(jìn)行更廣泛、更友好的合作。

xxxxxxx有限公司

董事長(zhǎng):xxx

篇9

無(wú)創(chuàng)機(jī)械通氣是急性左心衰患者的有效輔助治療方法之一，可明顯改善患者的呼吸狀況，保證有效通氣，可明顯緩解患者的急性左心衰狀況，改善心肌功能，進(jìn)而明顯提高患者的生活質(zhì)量，改善患者的預(yù)后[1-2]。為了探討護(hù)理干預(yù)在急性左心衰患者使用無(wú)創(chuàng)機(jī)械通氣治療中的影響，本院選取2011年11月～2013年11月診治的急性左心衰患者142例，均行無(wú)創(chuàng)機(jī)械通氣治療，根據(jù)護(hù)理方案分為兩組，行常規(guī)護(hù)理和護(hù)理干預(yù)，針對(duì)兩組患者的主訴恐懼情況、主訴配合情況、主訴并發(fā)癥情況進(jìn)行對(duì)比分析，現(xiàn)報(bào)告如下。

1.資料與方法

1.1資料

本院2011年11月～2013年11月診治的急性左心衰患者142例，年齡為47～81歲，平均年齡為67.3±5.9歲，其中男性108例，女性34例。患者均符合急性左心衰的診斷標(biāo)準(zhǔn)，且經(jīng)臨床表現(xiàn)和實(shí)驗(yàn)室檢查確診，排除患有其他器質(zhì)性病變、血液病、免疫性疾病的患者，均行無(wú)創(chuàng)機(jī)械通氣治療。根據(jù)護(hù)理方案分為兩組，常規(guī)護(hù)理患者71例為對(duì)照組，護(hù)理干預(yù)患者71例為觀察組，兩組患者的基礎(chǔ)資料（性別、年齡等）差異均無(wú)統(tǒng)計(jì)學(xué)意義（p>0.05），具有可比性。

1.2方法

觀察組患者實(shí)施護(hù)理干預(yù)：⑴基礎(chǔ)干預(yù)。護(hù)理人員采用和藹可親的語(yǔ)言和患者進(jìn)行交流，建立良好的醫(yī)患關(guān)系，取得患者的信任，通過(guò)溝通與交流，幫助患者消除焦慮、抑郁、恐懼、害怕、緊張、擔(dān)心等不良心理因素，幫助患者建立配合治療的信心和決心，建立良好的干預(yù)基礎(chǔ)。⑵情緒干預(yù)。向患者講解疾病的相關(guān)知識(shí)和治療的有效方法，使患者了解到疾病治療的目的和意義，使其可以正視疾病的治療，在治療過(guò)程中，患者出現(xiàn)恐懼感時(shí)要給予及時(shí)的安慰和鼓勵(lì)，采用支持性語(yǔ)言和肢體語(yǔ)言穩(wěn)定患者的情緒，提高患者的耐受性，消除患者的不安狀況，減輕患者的恐懼病癥。⑶行為干預(yù)。指導(dǎo)患者在治療過(guò)程中采用端坐位，將頭部與肩頸處于同一水平位置，將頭后仰，確保呼吸道通暢，佩戴合適的面部口鼻罩，調(diào)節(jié)松緊度，設(shè)定吸氣相壓力由6cmH2O開(kāi)始，設(shè)定呼氣相壓力由2cmH2O開(kāi)始，增到患者的耐受，要確?；颊叩拿娌科つw無(wú)受損，并在皮膚接觸部位放置紗布，減輕患者的壓迫感，在皮膚接觸部位涂抹凡士林，3h更換1次，每次20min，給予患者局部皮膚按摩等。⑷病情監(jiān)護(hù)。注意觀察患者的呼吸節(jié)律和心率狀況，確保主動(dòng)呼吸和呼吸機(jī)同步，注意保持患者的呼吸道通暢，在加濕器內(nèi)添加蒸餾水，將氣體濕化后進(jìn)入氣道，指導(dǎo)患者掌握正確的呼吸方法。對(duì)照組患者實(shí)施常規(guī)護(hù)理?；颊咴谥委熯^(guò)程中，給予患者常規(guī)的基礎(chǔ)護(hù)理，保證患者的病房通風(fēng)良好和環(huán)境的整潔衛(wèi)生，及時(shí)更換患者的床單被褥，只要患者實(shí)施正確的飲食和作息等。

1.3評(píng)定標(biāo)準(zhǔn)

主訴恐懼情況的評(píng)定標(biāo)準(zhǔn)：⑴輕度。患者不回避治療，無(wú)明顯的恐懼表現(xiàn)。⑵中度。患者有恐懼表現(xiàn)，曾試圖回避治療。⑶重度?；颊哂袕?qiáng)烈的恐懼表現(xiàn)，盡力回避治療，在護(hù)士幫助下才能完成治療。

主訴配合情況的評(píng)定標(biāo)準(zhǔn)：⑴積極?；颊呖梢苑e極主動(dòng)配合治療。⑵一般。患者可以基本配合治療。⑶較差?；颊咝枰谧o(hù)士幫助下勉強(qiáng)完成治療。

主訴并發(fā)癥情況的評(píng)定標(biāo)準(zhǔn)：⑴輕度?；颊呙娌渴軌禾幤つw發(fā)紅和疼痛，停機(jī)5～10min后可恢復(fù)正常。⑵中度。患者主訴有腹脹感，可耐受，面部受壓處皮膚發(fā)紅和疼痛，停機(jī)5～10min不能恢復(fù)正常。⑶重度?；颊咧髟V腹脹明顯，行胃腸減壓和肛管排氣后恢復(fù)，面部受壓處皮膚破損。

1.4統(tǒng)計(jì)學(xué)處理

數(shù)據(jù)資料均使用SPSS16.0統(tǒng)計(jì)學(xué)軟件進(jìn)行處理和分析，計(jì)數(shù)資料均使用χ2檢驗(yàn)，以p

2.結(jié)果

2.1兩組患者主訴恐懼情況比較

兩組患者主訴恐懼情況比較結(jié)果顯示（見(jiàn)表1），觀察組患者主訴恐懼情況明顯好于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義（p

表1兩組患者主訴恐懼情況比較（n，%）

2.2兩組患者主訴配合情況比較

兩組患者主訴配合情況比較結(jié)果顯示（見(jiàn)表2），觀察組患者主訴配合情況明顯好于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義（p

表2兩組患者主訴配合情況比較（n，%）

2.3兩組患者主訴并發(fā)癥情況比較

兩組患者主訴并發(fā)癥情況比較結(jié)果顯示（見(jiàn)表3），觀察組患者主訴并發(fā)癥情況明顯好于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義（p

表3兩組患者主訴并發(fā)癥情況比較（n，%）

3.討論

篇10

[關(guān)鍵詞] 西咪替??；干擾素；微量元素鋅；輪狀病毒感染性腹瀉

[中圖分類(lèi)號(hào)] R725.1 [文獻(xiàn)標(biāo)識(shí)碼] A [文章編號(hào)] 2095-0616（2017）08-40-03

[Abstract] Objective To curative effect analyze cimetidine and interferon combination of trace element zn in pediatric infectious diarrhea rotavirus. Methods 67 cases of children with infectious diarrhea rotavirus in our hospital from November 2015 to December 2016 were selected and divided into control group （implementation of cimetidine and interferon therapy） and treatment group （the implementation of cimetidine associated with interferon therapy trace element zine）. The curative effect of two groups were observed. Results The dehydration， stool and the recovery of body temperature and time of treatment group were significantly shorter than those of control group （P

[Key words] Cimetidine； Interferon； Trace element Zn； Infectious diarrhea rotavirus

臨床上，輪狀病毒感染性腹瀉在兒科中具有較高的發(fā)病率，引發(fā)本病的病原體主要為輪狀病毒，此病的主要臨床癥狀表現(xiàn)除了腹瀉之外同時(shí)普遍并發(fā)有脫水、發(fā)熱等癥狀，嚴(yán)重的甚至出現(xiàn)代謝紊亂以及酸中毒，通常好發(fā)于秋冬季節(jié)，若無(wú)法及時(shí)診斷并接受針對(duì)性治療，嚴(yán)重的甚至可直接引發(fā)死亡[1]?，F(xiàn)階段，臨床上對(duì)本病的發(fā)病機(jī)制尚無(wú)法明確，因而無(wú)統(tǒng)一的且具有明顯效果的治療標(biāo)準(zhǔn)[2]。為此，我院引入西咪替丁與干擾素聯(lián)合微量元素鋅治療，現(xiàn)將療效報(bào)道如下。

1 資料與方法

1.1 一般資料

67例均為我院自2015年11月～2016年12月期間收治的輪狀病毒感染性腹瀉患兒，納入標(biāo)準(zhǔn)：臨床癥狀均符合本病的癥狀表現(xiàn)，同時(shí)經(jīng)病原學(xué)檢查確診。經(jīng)醫(yī)院倫理委員會(huì)審批后，將67例患兒隨機(jī)分為治療組與對(duì)照組兩組，對(duì)照組32例，其中男17例，女15例；年齡0.7～4.5歲，平均年齡（1.6±0.8）歲。治療組35例，其中男19例，女16例；年齡0.8～4.4歲，平均年齡（1.6±0.7）歲。兩組患兒在基線(xiàn)資料方面對(duì)比差異無(wú)統(tǒng)計(jì)學(xué)意義（P>0.05），具有可比性。

1.2 方法

兩組均給予常規(guī)檢查，同時(shí)結(jié)合脫水的嚴(yán)重程度給予補(bǔ)液治療，給予發(fā)熱以及嘔吐者對(duì)癥治療，注意兩組均不能給予抗生素治療。基于此，對(duì)照組采用西咪替丁注射液（湖南漢森制藥股份有限公司；H43021799）10～15mg/（kg?d）治療，給藥方式為靜脈滴注，同時(shí)增加重組人干擾素α1b [安徽安科生物工程（集團(tuán)）股份有限公司；S20040010]治療，給藥方式為注射，劑量為100萬(wàn)U/次，1次/d。在此基礎(chǔ)上，治療組聯(lián)合葡萄糖酸鋅口服液（湖北福人金身藥業(yè)有限公司；H20065022）治療，給藥方式為口服，每支的含鋅量為0.03g，1支/d，兩組的療程均為10d。

1.3 觀察指標(biāo)及評(píng)定標(biāo)準(zhǔn)

記錄兩組大便及體溫恢復(fù)時(shí)間、脫水糾正時(shí)間。記錄兩組面色潮紅、煩躁以及腹瀉加重等不良反應(yīng)情況。對(duì)兩組治療效果進(jìn)行評(píng)估，若3d后，癥狀消失，同時(shí)糞便次數(shù)以及形狀均正常則評(píng)定為顯效；若3d后癥狀明顯緩解，同時(shí)糞便次數(shù)及形狀明顯好轉(zhuǎn)則評(píng)定為有效 ；若3d后癥狀未見(jiàn)任何緩解，同時(shí)糞便次數(shù)及形狀未見(jiàn)任何改善則評(píng)定為無(wú)效。總有效率=100%-無(wú)效率。

1.4 統(tǒng)計(jì)學(xué)分析

使用SPSS19.0統(tǒng)計(jì)學(xué)軟件處理數(shù)據(jù)，兩組計(jì)數(shù)資料對(duì)比行χ2檢驗(yàn)，兩組計(jì)量資料對(duì)比行t檢驗(yàn)，用P

2 結(jié)果

2.1 兩組治療基本情況比較

治療組脫水、大便以及體溫等的恢復(fù)時(shí)間均分別明顯短于對(duì)照組（P

2.2 兩組治療效果比較

治療組治療總有效率為97.14%，明顯高于對(duì)照組的71.88%（P

2.3 兩組不良反應(yīng)比較

治療組不良反應(yīng)發(fā)生率為2.86%，與對(duì)照組的不良反應(yīng)發(fā)生率6.26%對(duì)比差異無(wú)統(tǒng)計(jì)學(xué)意義（P>0.05），詳見(jiàn)表3。

3 討論

臨床上，感染性腹瀉屬于兒科中常見(jiàn)的一種腸道感染性疾病，出現(xiàn)腹部疼痛以及糞便不成形等為本病的主要癥狀表現(xiàn)[3-4]。人體小腸內(nèi)部的載膜絨毛上皮細(xì)胞中存在一種可以與輪狀病毒外殼中含有的VP4相互結(jié)合的病毒原體，因此小腸成為了輪狀病毒侵入的重要部位[5]。待病毒繼續(xù)侵入機(jī)體上皮細(xì)胞之后，便會(huì)誘發(fā)機(jī)體內(nèi)的大量非結(jié)構(gòu)蛋白糖基化，進(jìn)而引發(fā)細(xì)胞膜發(fā)生紊亂現(xiàn)象，例如鈣離子通透性，一旦機(jī)體細(xì)胞內(nèi)的鈣離子出現(xiàn)大量增多的現(xiàn)象，便會(huì)引發(fā)高鈣低氯癥狀，進(jìn)一步可增加病毒非結(jié)構(gòu)蛋白NSP3抑制蛋白正常合成的風(fēng)險(xiǎn)，進(jìn)而將影響小腸上皮細(xì)胞的運(yùn)行，嚴(yán)重的甚至可導(dǎo)致其脫落，極大的減少了雙糖轉(zhuǎn)化為單糖過(guò)程中所需的腸載膜上絨毛酶的數(shù)量，隨著時(shí)間的延長(zhǎng)，雙糖大量堆積在腸道內(nèi)，便極易增加腸腔內(nèi)滲透壓，進(jìn)而誘發(fā)腹瀉、嘔吐及脫水等癥狀，嚴(yán)重的可并發(fā)水電解質(zhì)紊亂以及酸中毒等嚴(yán)重威脅患兒生命的癥狀[6-7]。

西咪替丁是一種H2受體拮抗劑，能夠顯著抑制因組胺或者胃泌素引發(fā)的胃酸分泌，進(jìn)而避免受損腸黏膜長(zhǎng)期處在酸性環(huán)境中而對(duì)其起到保護(hù)作用，并有利于為絨毛的修復(fù)創(chuàng)造良好條件[8-9]。此外，此種藥物還具有免疫調(diào)節(jié)作用，能夠通過(guò)提高患兒機(jī)體內(nèi)的T淋巴細(xì)胞的轉(zhuǎn)化率而起到增強(qiáng)其免疫力的效果，進(jìn)而能夠避免炎癥反應(yīng)誘發(fā)的一系列繼發(fā)性損傷問(wèn)題[10-11]。干擾素則具有免疫調(diào)節(jié)以及抗病毒效應(yīng)等多種生理功能，在本病的治療過(guò)程中具有顯著的價(jià)值[12]。刷狀緣中大部分酶類(lèi)均對(duì)鋅元素存在較強(qiáng)的依賴(lài)性，同時(shí)鋅離子能夠顯著的抑制小腸黏膜的增生，且能夠促進(jìn)其完全角化，進(jìn)而能夠?qū)δc黏膜起到保護(hù)作用，此外，還可抑制胃腸激素分泌，增加腸內(nèi)鈉氯離子的吸收能力，進(jìn)而能夠?qū)δc腔的滲透壓起到降低的效果[13]。除此之外，鋅離子還具有免疫調(diào)節(jié)以及抑菌等多種功效。特別值得關(guān)注的是，我院在采用西咪替丁與干擾素常規(guī)治療的基礎(chǔ)上增加微量元素鋅的一個(gè)理論基礎(chǔ)是此類(lèi)型的患兒血清中鋅代謝有異常的現(xiàn)象[14-16]。

本研究中，治療組脫水、大便以及體溫等的的恢復(fù)時(shí)間均分別明顯短于對(duì)照組（P

綜上，將西咪替丁與干擾素聯(lián)合微量元素鋅應(yīng)用于輪狀病毒感染性腹瀉患兒的治療中，可以快速消除患兒的癥狀，促進(jìn)其康復(fù)，具有療效理想，安全性高的特點(diǎn)，值得臨床上推廣及應(yīng)用。

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